Epilepsy Research Today is a free monthly online journal that collates and summarizes the latest research about Epilepsy, including details on symptoms, causes, treatment, drugs, information.

Hyponatremia associated with repeated use of levetiracetam.

Nasrallah K, Silver B

Department of Neurology, Henry Ford Hospital, Detroit, Michigan 48202, USA. khalilnass@hotmail.com

Levetiracetam (LEV) is increasingly used as adjunctive anticonvulsant therapy because of apparent low toxicity. Somnolence, asthenia, headache, dizziness, and nervousness are the most frequently reported side effects (1). We describe a patient, predisposed to the development of the syndrome of inappropriate antidiuretic hormone secretion (SIADH), in whom hyponatremia developed after two challenges of LEV.

Published 10 June 2005 in Epilepsia, 46(6): 972-3.
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