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Ictal functional TCD for the lateralization of the seizure onset zone--a report of two cases.

Knake S, Haag A, Pilgramm G, Reis J, Klein KM, Hoeffken H, Bartenstein P, Oertel WH, Hamer HM, Rosenow F

Department of Neurology, Interdisciplinary Epilepsy Center, Philipps-University Marburg, Germany. knake@staff.uni-marburg.de

Ictal functional transcranial Doppler sonography (I-fTCD) was used to lateralize the ictal onset zone in the presurgical evaluation of two patients with temporal lobe epilepsy. In one patient, I-fTCD and ictal SPECT were performed simultaneously during EEG-monitoring. In both patients, results were concordant with the ictal SPECT findings, PET and semiology. I-fTCD seems to be an interesting new method to non-invasively lateralize the seizure onset zone with high temporal resolution. I-fTCD and SPECT may give complementary information to lateralize the seizure onset zone.

Published 2 November 2004 in Epilepsy Res, 62(1): 89-93.
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